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Explore pediatric brain tumor data visually

An interactive platform for exploring histopathology, spatial proteomics, and clinical data from pediatric brain tumours. It provides researchers and clinicians with an accessible environment to investigate patterns, uncover relationships, and translate complex datasets into visual insights.

About the data

This dashboard is based on two tissue microarrays (TMAs) containing tumor, adjacent healthy brain, and metastatic tissue. In total, they comprise 918 formalin-fixed paraffin-embedded (FFPE) tissue cores from 79 patients (78 pediatric, 1 adult). Cores with insufficient staining quality were excluded, leaving 797 usable cores from 277 unique specimens for exploration. Each core is annotated with multiple data modalities:

  • Virtual hematoxylin and eosin (H&E) stained images
  • Multiplex immunofluorescence (MxIF) images for selected protein markers
  • Patient-level metadata including diagnosis, treatment, and tumor location

TMA overview

Select which TMA to view:

Example tissue core

The following image shows a zoomed view of a single tissue core (A-1) from the TMA.

Explore the dashboard

This Home page is for information purposes only. Global filters are disabled here. Use the tabs below to explore the dataset interactively.

Oncoplot

See presence/absence patterns of markers and metadata across cores or patients.

Open oncoplot

Overview

High-level counts and distributions across diagnosis, location, treatment, and more.

Open overview

Cell-IF

Inspect MxIF overlays and single-cell summaries per core across available markers.

Open Cell-IF

Correlation

Compute Pearson/Spearman correlations and drill into scatter plots for selected markers.

Open correlation
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Institutions involved

Data Science programmeInstitute for Interactive TechnologiesCAIRODIPG/DMG Center Zurich

Project team

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Publication and contact

For details regarding the original preprint, please refer to: "Mapping Tumor Microenvironment and Treatment Response of Diffuse Midline Glioma Using Multiplexed Immunofluorescence and AI Models" preprint on bioRxiv (2025)

The study and dataset this dashboard is based on are summarized in the graphical abstract below.

Contact information

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